8v90

TtgR variant 3A7 with naltrexone

spinqualitylabelsall models 8v90, resolution 2.08Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8v90 is a 4 chain structure with sequence from Pseudomonas putida DOT-T1E. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.08Å Ligands: MG, YOE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TTGR_PSEPT Represses expression from the ttgABC operon promoter and its own expression. Binds to a promoter region between the divergently transcribed ttgR and ttgABC genes/operons; in the presence of chloramphenicol or tetracycline this binding no longer occurs and ttgR and ttgABC are derepressed. This suggests that TtgR binds these antibiotics.

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