8vtc

Crystal structure of Mycobacterium avium dihydrofolate reductase in complex with NADPH and trimethoprim

spinqualitylabelsall models 8vtc, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8vtc is a 1 chain structure with sequence from Mycobacterium avium. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2Å Ligands: CL, NDP, TOP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function O30463_MYCAV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]

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