8vu5

Cryo-EM structure of MPL bound to TPO

spinqualitylabelsall models 8vu5, resolution 3.39Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8vu5 is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.39Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TPO_MOUSE Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.[UniProtKB:P40225]

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