8w8f
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human co-transcriptional RNA capping enzyme RNGTT-CMTR1
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Structural highlights
FunctionMCE1_HUMAN Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. Contents | ||||||||||||||||||||
This page was last modified 08:03, 10 April 2024.