8w8y

Cryo-EM structure of gamma-MSH-MC3R-Gs_Nb35 complex

spinqualitylabelsall models 8w8y, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8w8y is a 6 chain structure with sequence from Bos taurus, Escherichia coli, Homo sapiens, Lama glama and Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.9Å Ligands: CA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MC3R_HUMAN Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.[UniProtKB:P33033]C562_ECOLX Electron-transport protein of unknown function.

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