8wpl
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Cryo-EM structure of the human TRPC1/C4 heteromer
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Structural highlights
FunctionTRPC1_HUMAN Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.[1] References
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This page was last modified 04:14, 17 October 2024.