8wpm

Cryo-EM structure of the human TRPC1/C4 heteromer in complex with Pico145

spinqualitylabelsall models 8wpm, resolution 3.43Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8wpm is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.43Å Ligands: CA, PJQ, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TRPC1_HUMAN Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

Proteopedia Page Contributors and Editors (what is this?)

OCA