Structural highlights
8x93 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | Electron Microscopy, Resolution 2.92Å |
| Ligands: | 3PE, CA, CLR, NAG, PT5, Y01 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
CACB3_HUMAN Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents (PubMed:8119293). Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity). Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity).[UniProtKB:P54287][UniProtKB:Q9MZL3][1]
References
- ↑ Collin T, Lory P, Taviaux S, Courtieu C, Guilbault P, Berta P, Nargeot J. Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit. Eur J Biochem. 1994 Feb 15;220(1):257-62. PMID:8119293 doi:10.1111/j.1432-1033.1994.tb18621.x
