8xqk
From Proteopedia
Jump to navigationJump to search
The Crystal Structure of Apaf from Biortus.
| ||||||||||||
Structural highlights
FunctionAPAF_HUMAN Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.[1] [2] References
| ||||||||||||||||||||
This page was last modified 12:12, 6 March 2024.