8y85

Human AE3 with NaHCO3- and DIDS

spinqualitylabelsall models 8y85, resolution 2.73Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8y85 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.73Å Ligands: 4KU, BCT Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease B3A3_HUMAN Familial short QT syndrome. The disease is caused by variants affecting the gene represented in this entry. Function B3A3_HUMAN Sodium-independent anion exchanger which mediates the electroneutral exchange of chloride for bicarbonate ions across the cell membrane (PubMed:29167417, PubMed:7923606). May be involved in the regulation of intracellular pH, and the modulation of cardiac action potential (PubMed:29167417).

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