8yar

ATAT-2 bound K40R MEC-12/MEC-7 microtubule

spinqualitylabelsall models 8yar, resolution 3.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8yar is a 6 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.6Å Ligands: ACO, G2P, GTP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TBA3_CAEEL Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. Component of the large-diameter neuronal microtubules which contains 15 protofilaments (PubMed:9885292). Plays a role in mechanosensory transduction (touch sensitivity) (PubMed:19652181, PubMed:9885292).

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