8z8a

Cryo-EM structure of the Lactate-bound human HCAR1-Gi1 complex

spinqualitylabelsall models 8z8a, resolution 2.82Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8z8a is a 5 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.82Å Ligands: 2OP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HCAR1_HUMAN Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.

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