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The Crystal Structure of Nudix Hydrolase from Bacillus methanolicus C1
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Structural highlights
FunctionACT_BACMT Involved in the activation of the NAD-dependent methanol dehydrogenase (MDH). MDH activation by Act involves hydrolytic removal of the nicotinamide mononucleotide (NMN) moiety of the NAD cofactor, changing its ping-pong type of reaction mechanism into a ternary complex reaction mechanism. It requires the presence of magnesium ions and is also able to use ADP-ribose.[1] [2] References
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This page was last modified 08:15, 4 June 2025.