8zyj

Cryo-EM structure of human testis-specific Na+,K+-ATPase alpha4 in ouabain-bound form

spinqualitylabelsall models 8zyj, resolution 2.37Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8zyj is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.37Å Ligands: BFD, CLR, MG, NA, NAG, OBN, PCW, Q7G Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function AT1A4_HUMAN This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Plays a role in sperm motility.

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