9au9
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Ternary complex of human DNA polymerase theta polymerase domain with a mismatched T:G base pair
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Structural highlights
FunctionDPOLQ_HUMAN Has a DNA polymerase activity on nicked double-stranded DNA and on a singly primed DNA template. The enzyme activity is resistant to aphidicolin, and inhibited by dideoxynucleotides. Exhibites a single-stranded DNA-dependent ATPase activity. Could be involved in the repair of interstrand cross-links.[1] References | ||||||||||||||||||||
This page was last modified 08:07, 5 March 2025.