9b4g

Structure of inhibitor-bound human PSS1

spinqualitylabelsall models 9b4g, resolution 2.87Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9b4g is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.87Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease PTSS1_HUMAN Lenz-Majewski hyperostotic dwarfism. The disease is caused by variants affecting the gene represented in this entry. Function PTSS1_HUMAN Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine (PubMed:19014349, PubMed:24241535). Catalyzes mainly the conversion of phosphatidylcholine (PubMed:19014349, PubMed:24241535). Also converts, in vitro and to a lesser extent, phosphatidylethanolamine (PubMed:19014349, PubMed:24241535).

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