9bu4

Crystal structure of an MKP5 mutant, Y435W, in complex with an allosteric inhibitor

spinqualitylabelsall models 9bu4, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9bu4 is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.9Å Ligands: CJA Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DUS10_HUMAN Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily.

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