9buc

Human calcitonin Receptor in complex with Gs and cagrilintide in the bypass conformation (repeat)

spinqualitylabelsall models 9buc, resolution 3.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9buc is a 6 chain structure with sequence from Homo sapiens and Lama glama. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.4Å Ligands: A1B90, GGL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CALCR_HUMAN This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

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