9bud

Human calcitonin Receptor in complex with Gs and cagrilintide in the CT-like conformation

spinqualitylabelsall models 9bud, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9bud is a 6 chain structure with sequence from Homo sapiens and Lama glama. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.5Å Ligands: A1B90, GGL, NH2 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CALCR_HUMAN This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.

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