9c0o

Crystal structure of DmCfp1 PHD finger bound to H3K4me3

spinqualitylabelsall models 9c0o, resolution 1.53Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9c0o is a 2 chain structure with sequence from Drosophila melanogaster and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.53Å Ligands: DMS, M3L, SO4, ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CXXC1_DROME Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3. Essential for Set1 association with chromatin and trimethylation of histone H3 at 'Lys-4' at transcription puffs. Additionally, is critical for general chromosomal association of Set1.

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