9cbe

Structure of a type III antifreeze protein isoform HPLC12 re-refined using standard protocols

spinqualitylabelsall models 9cbe, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9cbe is a 1 chain structure with sequence from Zoarces americanus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.9Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ANP12_ZOAAM Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth. Publication Abstract from PubMed The manuscript ;Modeling a unit cell: crystallographic refinement procedure using the biomolecular MD simulation platform Amber' presents a novel protein structure refinement method claimed to offer improvements over traditional techniques like Refmac5 and Phenix. Our re-evaluation suggests that while the new method provides improvements, traditional methods achieve comparable results with less computational effort. In some cases more complicated approaches to refinement of macromolecular structures are not necessary.,Dauter Z, Wlodawer A IUCrJ. 2024 Jul 1;11(Pt 4):643-644. doi: 10.1107/S2052252524005803. PMID:38958017 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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