9d9r

X-ray structure of ALX4 homeodomain dimer bound to DNA

spinqualitylabelsall models 9d9r, resolution 2.39Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9d9r is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.389Å Ligands: EDO Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease ALX4_HUMAN Isolated scaphocephaly;Parietal foramina;Frontonasal dysplasia with alopecia and genital anomaly;Potocki-Shaffer syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. Function ALX4_HUMAN Transcription factor involved in skull and limb development. Plays an essential role in craniofacial development, skin and hair follicle development.

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