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Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin candidate 2
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Structural highlights
FunctionITA5_HUMAN Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Contents | ||||||||||||||||||||
This page was last modified 10:54, 18 June 2025.