9e7m

In situ cryoEM structure of bacteriophage Ur-lambda tail tip complex

spinqualitylabelsall models 9e7m, resolution 3.37Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9e7m is a 36 chain structure with sequence from Escherichia phage Lambda. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.37Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TMP_LAMBD Serves as a ruler that controls the length of tail by stopping the tail tube polymerization and is probably released from the tail shaft during infection to facilitate DNA translocation into the host cell (PubMed:2150582). Assembles into a multimeric linear form possibly stabilized by the covering tail assembly proteins G and GT (PubMed:23911548). Its C-terminus fixes the tail tip complex (J, I, L, K), thereby forming the tail assembly initiator complex (PubMed:23911548). Tail tube proteins polymerize around tape measure protein, displacing the tail assembly protein G and GT (PubMed:23911548). When the tail reaches the length specified by the tape measure protein, it stops and becomes capped by the tail terminator protein (Probable). Upon tail assembly, tape measure protein is cleaved into a form called H*, that plays a role later during virion entry in a new cell (Probable). Once assembled, the virion is released and can infect new cells by binding to the entry receptor LambB (Probable). After opening of a pore on the external membrane, the entry protein H* protein is probably released in the periplasmic space for successful DNA injection (PubMed:23911548).[HAMAP-Rule:MF_04138]

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