Structural highlights
9e7n is a 4 chain structure with sequence from Plasmodium falciparum 3D7 and Vicugna pacos. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 2.49Å |
| Ligands: | BMA, GOL, MAN, NAG, PEG |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
P230_PLAF7 Gametocyte surface protein required for male/female gamete fusion. Also required for male gamete exflagellation and interaction with erythrocytes.[1]
References
- ↑ Eksi S, Czesny B, van Gemert GJ, Sauerwein RW, Eling W, Williamson KC. Malaria transmission-blocking antigen, Pfs230, mediates human red blood cell binding to exflagellating male parasites and oocyst production. Mol Microbiol. 2006 Aug;61(4):991-8. doi: 10.1111/j.1365-2958.2006.05284.x. PMID:16879650 doi:https://dx.doi.org/10.1111/j.1365-2958.2006.05284.x
