9ew8

Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors

spinqualitylabelsall models 9ew8, resolution 1.49Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9ew8 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.488Å Ligands: A1H7Q Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function B2LA1_HUMAN Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity).

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