9h6n

Flavin-dependent tryptophan 6-halogenase Thal in complex with 6-bromo-L-tryptophan

spinqualitylabelsall models 9h6n, resolution 2.33Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9h6n is a 2 chain structure with sequence from Streptomyces albogriseolus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.33Å Ligands: BTR, GOL, PO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TRP6H_STRAO Involved in the biosynthesis of thienodolin, a plant growth-regulating compound (PubMed:24692213). Catalyzes the chlorination of tryptophan (Trp) at C6 position to yield 6-chloro-tryptophan (PubMed:24692213, PubMed:33465708). It is also able to use bromide ions to generate monobrominated Trp (PubMed:33465708, PubMed:36259362). In vitro, accepts a wide range of amides and peptides carrying either L- or D-Trp at the N-terminus (PubMed:36259362).

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