9hmv
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Cryo-EM structure of SA2-SCC1 complex at 2.9 angstrom
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Structural highlights
FunctionSTAG2_HUMAN Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.[1] References
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This page was last modified 10:26, 3 September 2025.