9i52

Dopamine 1 receptor:GaS complex bound to 19B

spinqualitylabelsall models 9i52, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9i52 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.8Å Ligands: A1IZU Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DRD1_HUMAN Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.ADRB2_HUMAN Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

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