9ibk
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Solution NMR study of the titin I-band IgI domain I82 reveals conformational dynamics
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Structural highlights
FunctionTITIN_MOUSE Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase.[UniProtKB:Q8WZ42][1] [2] References
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This page was last modified 15:32, 10 June 2026.