9jvz

CryoEM structure of M. tuberculosis ClpP1P2 bound to bortezomib

spinqualitylabelsall models 9jvz, resolution 2.56Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9jvz is a 14 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.56Å Ligands: BO2 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function CLPP1_MYCTU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity).

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