9jxv

human translocase of the outer mitochondrial membrane (TOM complex)

spinqualitylabelsall models 9jxv, resolution 2.89Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9jxv is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.89Å Ligands: PC1 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease TOM40_HUMAN Early-onset autosomal dominant Alzheimer disease. Function TOM40_HUMAN Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022).

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