Structural highlights
Function
NCAP_BDV1 Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Targets viral NC to the nucleus. Could be involved in the transport of nucleoprotein particles from the nucleus to the cytoplasm. The nuclear export signal is masked by the interaction with the P protein.[1]
References
- ↑ Kobayashi T, Kamitani W, Zhang G, Watanabe M, Tomonaga K, Ikuta K. Borna disease virus nucleoprotein requires both nuclear localization and export activities for viral nucleocytoplasmic shuttling. J Virol. 2001 Apr;75(7):3404-12. PMID:11238866 doi:https://dx.doi.org/10.1128/JVI.75.7.3404-3412.2001
