9kcc

DNA duplex containing copper-mediated 5-fluorouracil-cytosine base pairs

spinqualitylabelsall models 9kcc, resolution 2.31Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9kcc is a 1 chain structure with sequence from Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.31Å Ligands: CU, UFP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Publication Abstract from PubMed Only mercury(II) and silver(I) ions are known to specifically bind to natural and naturally modified base pairs in duplex DNA to form metal-mediated base pairs. We found novel, specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil (FdU) in duplex DNA, forming C-Cu-FdU and FdU-Cu-C base pairs. Novel specific binding of copper ions to naturally modified base pairs involving 5-fluorouracil in duplex DNA.,Torigoe H, Hirabayashi K, Adachi S, Kondo J Dalton Trans. 2025 May 6;54(18):7208-7213. doi: 10.1039/d5dt00619h. PMID:40265694 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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