9kh2

Crystal structure of the first three zinc finger domains of ZBTB20 in complex with DNA

spinqualitylabelsall models 9kh2, resolution 2.59Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9kh2 is a 6 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.59Å Ligands: ZN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease ZBT20_HUMAN Intellectual disability-cataracts-calcified pinnae-myopathy syndrome. The disease is caused by variants affecting the gene represented in this entry. Function ZBT20_HUMAN May be a transcription factor that may be involved in hematopoiesis, oncogenesis, and immune responses (PubMed:11352661). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal (By similarity).[UniProtKB:Q8K0L9]

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