9kkj

Structure of Nectin-4 D1 domain in complex with the Fab fragment of 9MW2821 mAb

spinqualitylabelsall models 9kkj, resolution 3.26Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9kkj is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.26Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease NECT4_HUMAN Ectodermal dysplasia-pili torti-cutaneous syndactyly syndrome. The disease is caused by variants affecting the gene represented in this entry. Function NECT4_HUMAN Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.

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