Structural highlights
Function
SC6A6_MOUSE Mediates sodium- and chloride-dependent transport of taurine (PubMed:1465453, PubMed:30270321, PubMed:9375654). Can also mediate transport of hypotaurine, beta-alanine and gamma-aminobutyric acid (GABA) (PubMed:1465453, PubMed:30270321, PubMed:9375654).[1] [2] [3]
References
- ↑ Liu QR, López-Corcuera B, Nelson H, Mandiyan S, Nelson N. Cloning and expression of a cDNA encoding the transporter of taurine and beta-alanine in mouse brain. Proc Natl Acad Sci U S A. 1992 Dec 15;89(24):12145-9. PMID:1465453 doi:10.1073/pnas.89.24.12145
- ↑ Nishimura T, Higuchi K, Yoshida Y, Sugita-Fujisawa Y, Kojima K, Sugimoto M, Santo M, Tomi M, Nakashima E. Hypotaurine Is a Substrate of GABA Transporter Family Members GAT2/Slc6a13 and TAUT/Slc6a6. Biol Pharm Bull. 2018;41(10):1523-1529. PMID:30270321 doi:10.1248/bpb.b18-00168
- ↑ Vinnakota S, Qian X, Egal H, Sarthy V, Sarkar HK. Molecular characterization and in situ localization of a mouse retinal taurine transporter. J Neurochem. 1997 Dec;69(6):2238-50. PMID:9375654 doi:10.1046/j.1471-4159.1997.69062238.x
