9m1h

Cryo-EM structure of PGE2-EP1-Gq complex

spinqualitylabelsall models 9m1h, resolution 2.55Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9m1h is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.55Å Ligands: P2E Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PE2R1_HUMAN Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.

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