9m65

Crystal structure of the pathogen-secreted apoplastic GH12 xyloglucan-specific endoglucanase XEG1

spinqualitylabelsall models 9m65, resolution 2.59Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9m65 is a 1 chain structure with sequence from Phytophthora sojae strain P6497. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.59Å Ligands: A1ENU Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function XEG1_PHYSP Glycoside hydrolase that exhibits xyloglucanase activity (PubMed:26163574). Acts as an important virulence factor during P.sojae infection but also acts as a pathogen-associated molecular pattern (PAMP) in soybean and solanaceous species, where it can trigger defense responses including cell death. XEG1-induced cell death can be suppressed by P.sojae RxLR effectors. The PAMP activity is independent of its xyloglucanase activity (PubMed:26163574). XEG1 induces plant defense responses in a RLP kinase Serk3/Bak1-dependent manner in Nicotiana benthamiana. Moreover, the perception of XEG1 occurs independently of the perception of ethylene-inducing xylanase Eix2 in Tomato (PubMed:26163574). With truncated paralog XLP1, is required to elevate apoplastic sugar during P.sojae infection (PubMed:28082413).

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