| Structural highlights
Function
PP62_ASFB7 Essential for the correct assembly and maturation of the core of the virion.[1] Component of the core shell (PubMed:30185597). Binds to phosphatidylserine, which may enable the core shell binding with the inner membrane (PubMed:32519301).[2] [3] Component of the core shell (PubMed:30185597). Binds to phosphatidylserine and DNA, which may link the core shell to the inner membrane and to the viral nucleoid (PubMed:32451720).[4] [5] Component of the core shell.[6]
References
- ↑ Suarez C, Salas ML, Rodriguez JM. African swine fever virus polyprotein pp62 is essential for viral core development. J Virol. 2010 Jan;84(1):176-87. doi: 10.1128/JVI.01858-09. PMID:19846532 doi:https://dx.doi.org/10.1128/JVI.01858-09
- ↑ Alejo A, Matamoros T, Guerra M, Andres G. A Proteomic Atlas of the African Swine Fever Virus Particle. J Virol. 2018 Nov 12;92(23). pii: JVI.01293-18. doi: 10.1128/JVI.01293-18. Print , 2018 Dec 1. PMID:30185597 doi:https://dx.doi.org/10.1128/JVI.01293-18
- ↑ Li G, Fu D, Zhang G, Zhao D, Li M, Geng X, Sun D, Wang Y, Chen C, Jiao P, Cao L, Guo Y, Rao Z. Crystal structure of the African swine fever virus structural protein p35 reveals its role for core shell assembly. Protein Cell. 2020 Aug;11(8):600-605. doi: 10.1007/s13238-020-00730-w. PMID:32519301 doi:https://dx.doi.org/10.1007/s13238-020-00730-w
- ↑ Alejo A, Matamoros T, Guerra M, Andres G. A Proteomic Atlas of the African Swine Fever Virus Particle. J Virol. 2018 Nov 12;92(23). pii: JVI.01293-18. doi: 10.1128/JVI.01293-18. Print , 2018 Dec 1. PMID:30185597 doi:https://dx.doi.org/10.1128/JVI.01293-18
- ↑ Fu D, Zhao D, Zhang W, Zhang G, Li M, Zhang Z, Wang Y, Sun D, Jiao P, Chen C, Guo Y, Rao Z. Structure of African swine fever virus p15 reveals its dual role for membrane-association and DNA binding. Protein Cell. 2020 Aug;11(8):606-612. doi: 10.1007/s13238-020-00731-9. PMID:32451720 doi:https://dx.doi.org/10.1007/s13238-020-00731-9
- ↑ Alejo A, Matamoros T, Guerra M, Andres G. A Proteomic Atlas of the African Swine Fever Virus Particle. J Virol. 2018 Nov 12;92(23). pii: JVI.01293-18. doi: 10.1128/JVI.01293-18. Print , 2018 Dec 1. PMID:30185597 doi:https://dx.doi.org/10.1128/JVI.01293-18
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