9mnn
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Crystal structure of L. monocytogenes MenD with Mg2+ and intermediate I bound
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Structural highlights
FunctionA0A0H3GD77_LISM4 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).[HAMAP-Rule:MF_01659] Contents | ||||||||||||||||||||
This page was last modified 05:46, 30 July 2025.