9mrs

Crystal structure of human MMACHC in complex with MMADHC and B12

spinqualitylabelsall models 9mrs, resolution 3.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9mrs is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 3.4Å Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease MMAC_HUMAN Methylmalonic acidemia with homocystinuria, type cblC. The disease is caused by mutations affecting the gene represented in this entry. Function MMAC_HUMAN May be involved in the binding and intracellular trafficking of cobalamin (vitamin B12).

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