9mzh
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Cryo-EM structure of the Nipah virus polymerase containing the connecting domain
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Structural highlights
FunctionPHOSP_NIPAV Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W. Contents | ||||||||||||||||||
This page was last modified 05:46, 30 July 2025.