Structural highlights
9n6v is a 10 chain structure with sequence from Saccharomyces cerevisiae S288C. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | Electron Microscopy, Resolution 3.16Å |
| Ligands: | ATP, GTP, MG, SEP, ZN |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
KRR1_YEAST Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.[1] [2] [3] [4]
References
- ↑ Gromadka R, Rytka J. The KRR1 gene encodes a protein required for 18S rRNA synthesis and 40S ribosomal subunit assembly in Saccharomyces cerevisiae. Acta Biochim Pol. 2000;47(4):993-1005. PMID:11996121
- ↑ Sasaki T, Toh-E A, Kikuchi Y. Yeast Krr1p physically and functionally interacts with a novel essential Kri1p, and both proteins are required for 40S ribosome biogenesis in the nucleolus. Mol Cell Biol. 2000 Nov;20(21):7971-9. PMID:11027267
- ↑ Gromadka R, Karkusiewicz I, Rempola B, Rytka J. Functional and physical interactions of Krr1p, a Saccharomyces cerevisiae nucleolar protein. Acta Biochim Pol. 2004;51(1):173-87. PMID:15094838 doi:https://dx.doi.org/045101173
- ↑ Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ. The small-subunit processome is a ribosome assembly intermediate. Eukaryot Cell. 2004 Dec;3(6):1619-26. PMID:15590835 doi:https://dx.doi.org/10.1128/EC.3.6.1619-1626.2004
