9n8y | pdb_00009n8y

Cryo EM Structure of Full Length mGluR8 Bound to Agonist L-AP4 and PAM VU6005649

spinqualitylabelsall models 9n8y, resolution 2.76Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9n8y is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.76Å Ligands: A1BWG, E7P Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function GRM8_HUMAN G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

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