9nea

Human polymerase epsilon bound to PCNA and DNA with a pre-existing mismatch in the blocked conformation II

spinqualitylabelsall models 9nea, resolution 3.81Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9nea is a 6 chain structure with sequence from Homo sapiens and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.81Å Ligands: MG, PST Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease DPOE1_HUMAN Facial dysmorphism - immunodeficiency - livedo - short stature. Disease susceptibility is associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function DPOE1_HUMAN Participates in DNA repair and in chromosomal DNA replication.

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