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Structure of human substrate-free 26S proteasome in the presence of ATPgS and MG-132,SA-like state (composite map)
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Structural highlights
FunctionPRS7_HUMAN The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.[1] References | ||||||||||||||||||||
This page was last modified 18:12, 7 May 2025.