9nov

Human sweet taste receptor (TAS1R2 + TAS1R3) VFT domains bound to sucralose

spinqualitylabelsall models 9nov, resolution 3.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9nov is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.3Å Ligands: NAG, PRD_900090, RRJ, RRY Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function TS1R3_HUMAN Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.

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