9o04

CryoEM structure of the FBXO42-CCDC6-PP2Ac degradasome

spinqualitylabelsall models 9o04, resolution 3.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9o04 is a 14 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.2Å Ligands: MLL, MN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease CCDC6_HUMAN Differentiated thyroid carcinoma. A chromosomal aberration involving CCDC6 is found in papillary thyroid carcinomas (PTCs). Inversion inv(10)(q11.2;q21) generates the RET/CCDC6 (PTC1) oncogene. Function CCDC6_HUMAN

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