9o85

Cryo-EM structure of KCa2.2_I/calmodulin channel in complex with rimtuzalcap

spinqualitylabelsall models 9o85, resolution 3.13Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 9o85 is a 8 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 3.13Å Ligands: A1B92, CA, K Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function KCNN2_RAT Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

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